Structural Imaging Changes and Behavioral Correlates in Patients with Crohn's Disease in Remission.

ABSTRACT: Background: Crohn's disease (CD) is a subtype of inflammatory bowel disease caused by immune-mediated inflammation in the gastrointestinal tract. The extent of morphologic brain alterations and their associated cognitive and affective impairments remain poorly characterized. Aims: We used magnetic resonance imaging to identify structural brain differences between patients with Crohn's disease in remission compared to age-matched healthy controls and evaluated for structural-behavioral correlates. Methods: Nineteen patients and 20 healthy, age-matched controls were recruited in the study. Group differences in brain morphometric measures and correlations between brain measures and performance on a cognitive task, the verbal fluency (VF) task, were examined. Correlations

SUBMITTER: Nair VA 

PROVIDER: S-EPMC5025433 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature