Native myocardial longitudinal (T1 ) relaxation time: Regional, age, and sex associations in the healthy adult heart.

ABSTRACT:

Purpose

To use magnetic resonance imaging (MRI) at two field strengths to assess healthy adults' regional myocardial noncontrast (native) T1 relaxation time distribution, and global myocardial native T1 between sexes and across age groups.

Materials and methods

In all, 84 healthy volunteers underwent MRI at 1.5T and 3.0T. T1 maps were acquired in three left ventricular short axis slices using an optimized modified Look-Locker inversion recovery investigational prototype sequence. T1 measurements in msec were calculated from 16 regions-of-interest, and a global T1 value from all evaluable segments per subject. Associations were assessed with a multivariate linear regression model.

Results

In total, 1297 (96.5%) segments were evaluable at 1.5T and 1263 (94.0%) segments

SUBMITTER: Rauhalammi SM 

PROVIDER: S-EPMC5025725 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature