Multitype Infections With Human Papillomavirus: Impact of Human Immunodeficiency Virus Coinfection.

ABSTRACT:

Background

Human immunodeficiency virus (HIV) infection predisposes women to genital coinfection with human papillomaviruses (HPVs). Concurrent infection with multiple HPV types has been documented, but its frequency, correlates, and impact on development of precancer are poorly defined in HIV-seropositive women.

Methods

Human immunodeficiency virus-seropositive women and -seronegative comparison women were enrolled in a cohort study and followed every 6 months from 1994 to 2006. Cervicovaginal lavage samples were tested for HPV types using polymerase chain reaction amplification with MY09/MY11 consensus primers followed by hybridization with consensus and HPV type-specific probes. Analyses were performed using generalized estimating equations.

Results

Multitype HPV i

SUBMITTER: Massad L 

PROVIDER: S-EPMC5026395 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature