Aberrant prefrontal beta oscillations predict episodic memory encoding deficits in schizophrenia.

ABSTRACT: Verbal episodic memory is one of the core cognitive functions affected in patients with schizophrenia (SZ). Although this verbal memory impairment in SZ is a well-known finding, our understanding about its underlying neurophysiological mechanisms is rather scarce. Here we address this issue by recording brain oscillations during a memory task in a sample of healthy controls and patients with SZ. Brain oscillations represent spectral fingerprints of specific neurocognitive operations and are therefore a promising tool to identify neurocognitive mechanisms that are affected by SZ. Healthy controls showed a prominent suppression of left prefrontal beta oscillatory activity during successful memory formation, which replicates several previous oscillatory memory studies. In contrast, patients f

SUBMITTER: Meconi F 

PROVIDER: S-EPMC5026693 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature