Comparison of Frailty Phenotypes for Prediction of Mortality, Incident Falls, and Hip Fracture in Older Women.

ABSTRACT:

Objectives

To compare the ability of the commonly used Women's Health Initiative (WHI) and Cardiovascular Health Study (CHS) frailty phenotypes to predict falls, hip fracture, and death in WHI Clinical Trial participants aged 65 and older.

Design

Longitudinal cohort study.

Setting

WHI Clinical Trial.

Participants

Participants with data for WHI and CHS frailty phenotypes (N = 3,558).

Measurements

Frailty was operationally defined in the CHS as the presence of three or more of weight loss, poor energy, weakness, slowness, and low physical activity. WHI operationalized frailty similarly but with the RAND-36 physical function scale substituted for slowness and weakness (RAND-36 physical function scale score <13 = 2 points, 13-78 = 1 point, >78 = 0 points). F

SUBMITTER: Zaslavsky O 

PROVIDER: S-EPMC5026871 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature