Preliminary investigation of multiparametric strain Z-score (MPZS) computation using displacement encoding with simulated echoes (DENSE) and radial point interpretation method (RPIM).

ABSTRACT:

Purpose

To describe and assess an automated normalization method for identifying sentinel (septal) regions of myocardial dysfunction in nonischemic, nonvalvular dilated cardiomyopathy (DCM), using an unprecedented combination of the navigator-gated 3D spiral displacement encoding with stimulated echoes (DENSE) magnetic resonance imaging (MRI), radial point interpolation (RPIM) and multiparametric strain z-score (MPZS).

Materials and methods

Navigator-gated 3D spiral DENSE, in a 1.5T MRI machine, was used for acquiring the displacement encoded complex images, MR Analytical Software System (MASS) for automated boundary detection and automated meshfree RPIM for left-ventricular (LV) myocardial strain computation to analyze MPZS in 36 subjects (with n = 17 DCM patients). Pearson

SUBMITTER: Kar J 

PROVIDER: S-EPMC5028227 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature