Muscle size explains low passive skeletal muscle force in heart failure patients.

ABSTRACT:

Background

Alterations in skeletal muscle function and architecture have been linked to the compromised exercise capacity characterizing chronic heart failure (CHF). However, how passive skeletal muscle force is affected in CHF is not clear. Understanding passive force characteristics in CHF can help further elucidate the extent to which altered contractile properties and/or architecture might affect muscle and locomotor function. Therefore, the aim of this study was to investigate passive force in a single muscle for which non-invasive measures of muscle size and estimates of fiber force are possible, the soleus (SOL), both in CHF patients and age- and physical activity-matched control participants.

Methods

Passive SOL muscle force and size were obtained by means of a novel

SUBMITTER: Panizzolo FA 

PROVIDER: S-EPMC5028761 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature