β blockers and mortality after myocardial infarction in patients without heart failure: multicentre prospective cohort study.

ABSTRACT:

Objective

To assess the association between early and prolonged β blocker treatment and mortality after acute myocardial infarction.

Design

Multicentre prospective cohort study.

Setting

Nationwide French registry of Acute ST- and non-ST-elevation Myocardial Infarction (FAST-MI) (at 223 centres) at the end of 2005.

Participants

2679 consecutive patients with acute myocardial infarction and without heart failure or left ventricular dysfunction.

Main outcome measures

Mortality was assessed at 30 days in relation to early use of β blockers (≤48 hours of admission), at one year in relation to discharge prescription, and at five years in relation to one year use.

Results

β blockers were used early in 77% (2050/2679) of patients, were prescribed at disch

SUBMITTER: Puymirat E 

PROVIDER: S-EPMC5029148 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature