Alpha oscillation neurofeedback modulates amygdala complex connectivity and arousal in posttraumatic stress disorder.

ABSTRACT:

Objective

Electroencephalogram (EEG) neurofeedback aimed at reducing the amplitude of the alpha-rhythm has been shown to alter neural networks associated with posttraumatic stress disorder (PTSD), leading to symptom alleviation. Critically, the amygdala is thought to be one of the central brain regions mediating PTSD symptoms. In the current study, we compare directly patterns of amygdala complex connectivity using fMRI, before and after EEG neurofeedback, in order to observe subcortical mechanisms associated with behavioural and alpha oscillatory changes among patients.

Method

We examined basolateral (BLA), centromedial (CMA), and superficial (SFA) amygdala complex resting-state functional connectivity using a seed-based approach via SPM Anatomy Toolbox. Amygdala complex co

SUBMITTER: Nicholson AA 

PROVIDER: S-EPMC5030332 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature