Eu³⁺ doped α-sodium gadolinium fluoride luminomagnetic nanophosphor as a bimodal nanoprobe for high-contrast in vitro bioimaging and external magnetic field tracking applications.

ABSTRACT: Herein, we introduce a novel strategy for the synthesis of Eu³⁺ doped α-sodium gadolinium fluoride (α-NaGd_0.88F₄:Eu_0.12³⁺) based luminomagnetic nanophosphors using hydrothermal route. The synthesized nanophosphor has exceptional luminescent and paramagnetic properties in a single host lattice, which is highly desirable for biomedical applications. This highly luminescent nanophosphor with an average particle size ∼ 5±3 nm enables high-contrast fluorescent imaging with decreased light scattering. In vitro cellular uptake is shown by fluorescent microscopy that envisages the characteristic hypersensitive red emission of Eu³⁺ doped α-sodium gadolinium fluoride centered at 608 nm (⁵D₀-⁷F

SUBMITTER: Singh S 

PROVIDER: S-EPMC5031147 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature