Meta-analysis of colorectal cancer follow-up after potentially curative resection.

ABSTRACT:

Background

After potentially curative resection of primary colorectal cancer, patients may be monitored by measurement of carcinoembryonic antigen and/or CT to detect asymptomatic metastatic disease earlier.

Methods

A systematic review and meta-analysis was conducted to find evidence for the clinical effectiveness of monitoring in advancing the diagnosis of recurrence and its effect on survival. MEDLINE (Ovid), Embase, the Cochrane Library, Web of Science and other databases were searched for randomized comparisons of increased intensity monitoring compared with a contemporary standard policy after resection of primary colorectal cancer.

Results

There were 16 randomized comparisons, 11 with published survival data. More intensive monitoring advanced the diagnosis of r

SUBMITTER: Mokhles S 

PROVIDER: S-EPMC5031212 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature