Characterization of a Zika Virus Isolate from Colombia.

ABSTRACT:

Background

Zika virus (Flavivirus genus) is the first mosquito-borne virus known to cause high rates of microcephaly and abortion in humans. Typically, Zika virus causes a self-limiting, systemic illness; however, the current outbreak of Zika virus in the Americas has been associated with increased rates of fetal malformations and Guillain-Barré syndrome. Very few Zika virus isolates have been described in the literature, and live viruses are needed to perform studies of pathogenesis and to develop vaccines and treatments.

Methodology/clinical findings

We isolated Zika virus, strain FLR, directly from the serum of an individual infected in Barranquilla, Colombia (December, 2015). Here, we describe the patient's clinical course and characterize strain FLR by its growth charac

SUBMITTER: Lahon A 

PROVIDER: S-EPMC5031432 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature