Gestational weight gain, prepregnancy body mass index and offspring attention-deficit hyperactivity disorder symptoms and behaviour at age 10.

ABSTRACT:

Objective

To assess offspring attention-deficit hyperactivity disorder (ADHD) symptoms and emotional/behavioural impairments at age 10 years in relation to maternal gestational weight gain (GWG) and prepregnancy body mass index (BMI).

Design and setting

Longitudinal birth cohort from Magee-Womens Hospital, Pittsburgh, Pennsylvania (enrolled 1983-86).

Population

Mother-infant dyads (n = 511) were followed through pregnancy to 10 years.

Methods

Self-reported total GWG was converted to gestational-age-standardised z-scores. Multivariable linear and negative binomial regressions were used to estimate effects of GWG and BMI on outcomes.

Main outcome measures

Child ADHD symptoms were assessed with the Conners' Continuous Performance Test. Child behaviour was a

SUBMITTER: Pugh SJ 

PROVIDER: S-EPMC5031500 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature