RNA-Seq Analysis Reveals Candidate Targets for Curcumin against Tetranychus cinnabarinus.

ABSTRACT: Tetranychus cinnabarinus is an important agricultural pest with a broad host range. We previously identified curcumin as a promising acaricidal compound against T. cinnabarinus. However, the acaricidal mechanism of curcumin remains unknown. In this study, RNA-seq was employed to analyze the transcriptome changes in T. cinnabarinus treated with curcumin or the solvent. A total of 105,706,297 clean sequence reads were generated by sequencing, with more than 90% of the reads successfully mapped to the reference sequence. The RNA-seq identified 111 and 96 differentially expressed genes between curcumin- and solvent-treated mites at 24 and 48 h after treatment, respectively. GO enrichment analysis of differentially expressed genes showed that the cellular process was the do

SUBMITTER: Liu X 

PROVIDER: S-EPMC5031819 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature