A traceless directing group for C-H borylation.

ABSTRACT: Not a trace: Borylation of the nitrogen in nitrogen heterocycles or anilines provides a traceless directing group for subsequent catalytic C-H borylation. Selectivities that previously required Boc protection can be achieved; furthermore, the NBpin directing group can be installed and removed in-situ, and product yields are substantially higher. Boc=tert-butoxycarbonyl, pin=pinacolato.

SUBMITTER: Preshlock SM 

PROVIDER: S-EPMC5032627 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature