Sizing and Discovery of Nanosized Polyoxometalate Clusters by Mass Spectrometry.

ABSTRACT: Ion mobility-mass spectrometry (IM-MS) is a powerful technique for structural characterization, e.g., sizing and conformation, particularly when combined with quantitative modeling and comparison to theoretical values. Traveling wave IM-MS (TW-IM-MS) has recently become commercially available to nonspecialist groups and has been exploited in the structural study of large biomolecules, however reliable calibrants for large anions have not been available. Polyoxometalate (POM) species-nanoscale inorganic anions-share many of the facets of large biomolecules, however, the full potential of IM-MS in their study has yet to be realized due to a lack of suitable calibration data or validated theoretical models. Herein we address these limitations by reporting DT-IM (drift tube) data for a set of

SUBMITTER: Surman AJ 

PROVIDER: S-EPMC5033399 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature