The synergistic effect of TiO₂ nanoporous modification and platelet-rich plasma treatment on titanium-implant stability in ovariectomized rats.

ABSTRACT: For several decades, titanium and its alloys have been commonly utilized for endosseous implantable materials, because of their good mechanical properties, chemical resistance, and biocompatibility. But associated low bone mass, wear and loss characteristics, and high coefficients of friction have limited their long-term stable performance, especially in certain abnormal bone-metabolism conditions, such as postmenopausal osteoporosis. In this study, we investigated the effects of platelet-rich plasma (PRP) treatment and TiO₂ nanoporous modification on the stability of titanium implants in osteoporotic bone. After surface morphology, topographical structure, and chemical changes of implant surface had been detected by scanning electron microscopy (SEM), atomic force microscopy, c

SUBMITTER: Jiang N 

PROVIDER: S-EPMC5033614 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature