Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula.

ABSTRACT: RNA sequencing has allowed high-throughput screening of differential gene expression in many tissues and organisms. Xenopus laevis is a classical embryological and cell-free extract model system, but its genomic sequence had been lacking due to difficulties arising from allotetraploidy. There is currently much excitement surrounding the release of the completed X. laevis genome (version 9.1) by the Joint Genome Institute (JGI), which provides a platform for genome-wide studies. Here we present a deep RNA-seq dataset of transcripts expressed in dorsal and ventral lips of the early Xenopus gastrula embryo using the new genomic information, which was further annotated by blast searches against the human proteome. Overall, our findings confirm previous results from differential screenings usin

SUBMITTER: Ding Y 

PROVIDER: S-EPMC5033668 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature