The Effect of Supplemental Oxygen in Obesity Hypoventilation Syndrome.

ABSTRACT:

Study objectives

Low flow supplemental oxygen is commonly prescribed to patients with obesity hypoventilation syndrome (OHS). However, there is a paucity of data regarding its efficacy and safety. The objective of this study was to assess the medium-term treatment efficacy of adding supplemental oxygen therapy to commonly prescribed treatment modalities in OHS.

Methods

In this post hoc analysis of a previous randomized controlled trial, we studied 302 sequentially screened OHS patients who were randomly assigned to noninvasive ventilation, continuous positive airway pressure, or lifestyle modification. Outcomes at 2 mo included arterial blood gases, symptoms, quality of life, blood pressure, polysomnography, spirometry, 6-min walk distance, and hospital resource utili

SUBMITTER: Masa JF 

PROVIDER: S-EPMC5033740 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature