Coding Properties of Three Intrinsically Distinct Retinal Ganglion Cells under Periodic Stimuli: A Computational Study.

ABSTRACT: As the sole output neurons in the retina, ganglion cells play significant roles in transforming visual information into spike trains, and then transmitting them to the higher visual centers. However, coding strategies that retinal ganglion cells (RGCs) adopt to accomplish these processes are not completely clear yet. To clarify these issues, we investigate the coding properties of three types of RGCs (repetitive spiking, tonic firing, and phasic firing) by two different measures (spike-rate and spike-latency). Model results show that for periodic stimuli, repetitive spiking RGC and tonic RGC exhibit similar spike-rate patterns. Their spike- rates decrease gradually with increased stimulus frequency, moreover, variation of stimulus amplitude would change the two RGCs' spike-rate patterns. F

SUBMITTER: Wang L 

PROVIDER: S-EPMC5033956 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature