Region-specific growth restriction of brain following preterm birth.

ABSTRACT: Regional brain sizes of very-preterm infants at term-equivalent age differ from those of term-born peers, which have been linked with later cognitive impairments. However, dependence of regional brain volume loss on gestational age has not been studied in detail. To investigate the spatial pattern of brain growth in neonates without destructive brain lesions, head MRI of 189 neonates with a wide range of gestational age (24-42 weeks gestation) was assessed using simple metrics measurements. Dependence of MRI findings on gestational age at birth (Age_birth) and the corrected age at MRI scan (Age_MRI) were assessed. The head circumference was positively correlated with Age_MRI, but not Age_birth. The bi-parietal width, deep grey matter area and the tra

SUBMITTER: Iwata S 

PROVIDER: S-EPMC5034268 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature