Grandmother's smoking when pregnant with the mother and asthma in the grandchild: the Norwegian Mother and Child Cohort Study.

ABSTRACT:

Background

A trans-generational influence of prenatal tobacco smoke exposure on asthma development has been proposed but the evidence remains sparse.

Methods

We examined the grandmother's smoking when pregnant with the mother in relation to asthma outcomes in the grandchild (current asthma at 36 months (N=53 169, cases=3013), current asthma at 7 years (N=25 394, cases=1265) and dispensed asthma medications at 7 years in the Norwegian Prescription Database (N=45 607, cases=1787)) within the Norwegian Mother and Child Cohort Study (MoBa). We calculated adjusted RR (adj. RR) and 95% CIs using log binomial regression.

Results

A total of 23.5% of mothers reported that their mother smoked when pregnant with them. The grandmother's smoking when pregnant with the mother was p

SUBMITTER: Magnus MC 

PROVIDER: S-EPMC5034931 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature