Mycoplasma agalactiae Induces Cytopathic Effects in Infected Cells Cultured In Vitro.

ABSTRACT: Mycoplasma agalactiae is the etiological agent of the contagious agalactia syndrome in sheep and goats and causes significant economic losses worldwide. Yet the mechanism of pathogenesis is largely unknown. Even whole-genome sequence analysis of its pathogenic type strain did not lead to any conclusions regarding its virulence or pathogenicity factors. Although inflammation and tissue destruction at the local site of M. agalactiae infection are largely considered as effects of the host immune response, the direct effect of the agent on host cells is not completely understood. The aim of this study was to investigate the effect of M. agalactiae infection on the quality and viability of host cells in vitro. Changes in cell morphology including cell elongation, cytoplasm shrinkage and membran

SUBMITTER: Hegde S 

PROVIDER: S-EPMC5035028 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature