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ABSTRACT: Background
The Agatston score, commonly used to quantify coronary artery calcification (CAC), is determined by the plaque area and density. Despite an excellent predictability of the Agatston score for cardiovascular events, the density of CAC has never been studied in patients with pre-dialysis chronic kidney disease (CKD). This study aimed to analyze the CAC density and its association with serum mineral levels in CKD.Methods
We enrolled patients with pre-dialysis CKD who had diabetes mellitus, prior cardiovascular disease history, elevated low-density lipoprotein cholesterol levels, or smoking history. The average CAC density was calculated by dividing the Agatston score by the total area of CAC.Results
The mean estimated glomerular filtration rate (eGFR) of 109
SUBMITTER: Sakaguchi Y
PROVIDER: S-EPMC5035086 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature