Diagnostic workup and costs of a single supplemental molecular breast imaging screen of mammographically dense breasts.

ABSTRACT:

Objective

The purpose of this study was to examine additional diagnostic workup and costs generated by addition of a single molecular breast imaging (MBI) examination to screening mammography for women with dense breasts.

Subjects and methods

Women with mammographically dense breasts presenting for screening mammography underwent adjunct MBI performed with 300 MBq (99m)Tc-sestamibi and a direct-conversion cadmium-zinc-telluride dual-head gamma camera. All subsequent imaging tests and biopsies were tracked for a minimum of 1 year. The positive predictive value of biopsies performed (PPV3), benign biopsy rate, cost per patient screened, and cost per cancer detected were determined.

Results

A total of 1651 women enrolled in the study. Among the 1585 participants with com

SUBMITTER: Hruska CB 

PROVIDER: S-EPMC5036572 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature