Evaluating the relationship between cannabis use and IQ in youth and young adults at clinical high risk of psychosis.

ABSTRACT: Among people with psychosis, those with a history of cannabis use show better cognitive performance than those who are cannabis naïve. It is unknown whether this pattern is present in youth at clinical high risk (CHR) of psychosis. We evaluated relationships between IQ and cannabis use while controlling for use of other substances known to impact cognition in 678 CHR and 263 healthy control (HC) participants. IQ was estimated using the Vocabulary and Block Design subtests of the Wechsler Abbreviated Scale of Intelligence. Drug and alcohol use severity and frequency were assessed with the Alcohol and Drug Use Scale, and we inquired participants' age at first use. CHR were further separated into early and late age at onset of cannabis use sub-groups, and low-, moderate- and high-frequency su

SUBMITTER: Buchy L 

PROVIDER: S-EPMC5037441 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature