Reproducibility assessment of brain responses to visual food stimuli in adults with overweight and obesity.

ABSTRACT:

Objective

The brain's reward system influences ingestive behavior and subsequently obesity risk. Functional magnetic resonance imaging (fMRI) is a common method for investigating brain reward function. This study sought to assess the reproducibility of fasting-state brain responses to visual food stimuli using BOLD fMRI.

Methods

A priori brain regions of interest included bilateral insula, amygdala, orbitofrontal cortex, caudate, and putamen. Fasting-state fMRI and appetite assessments were completed by 28 women (n = 16) and men (n = 12) with overweight or obesity on 2 days. Reproducibility was assessed by comparing mean fasting-state brain responses and measuring test-retest reliability of these responses on the two testing days.

Results

Mean fasting-state brain resp

SUBMITTER: Drew Sayer R 

PROVIDER: S-EPMC5039059 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature