Ontology highlight
ABSTRACT:
SUBMITTER: Vainauskas S
PROVIDER: S-EPMC5039751 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Vainauskas Saulius S Duke Rebecca M RM McFarland James J McClung Colleen C Ruse Cristian C Taron Christopher H CH
Scientific reports 20160928
A novel fucose-binding lectin (SL2-1) from the bacterium Streptomyces rapamycinicus was identified by analysis of metagenomic DNA sequences. SL2-1 belongs to a new group of bacterial fucose-specific lectins that have no similarity to known bacterial fucose-binding proteins, but are related to certain eukaryotic fucose-binding lectins. The 17 kDa protein was expressed recombinantly in E. coli and purified by affinity chromatography. Glycan microarray analysis with fluorescently labeled recombinan ...[more]