"Obesity Paradox" in Acute Respiratory Distress Syndrome: Asystematic Review and Meta-Analysis.

ABSTRACT:

Background

It is unclear whether an "obesity paradox" exists in the respiratory system, especially in acute respiratory distress syndrome (ARDS) and acute lung injury (ALI). Previous studies have postulated a causal relation between obesity and ARDS/ALI but have lacked power to form a definitive conclusion.

Objective

To investigate the relationships between obesity, ARDS/ALIrisk, and mortality.

Methods

A systematic search current to April 2016 was performed in Pubmed, EMBASE, Medline, Cochrane databases to find relevant studies. All studies that estimate the effect of obesity in the morbidity and mortality of ARDS/ALI were included.

Results

A total of 24 studies including 9,187,248 subjects were analyzed. The combined results from 16 studies that examined the e

SUBMITTER: Zhi G 

PROVIDER: S-EPMC5042414 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature