Pragmatic Trials in Maintenance Dialysis: Perspectives from the Kidney Health Initiative.

ABSTRACT: Pragmatic clinical trials are conducted under the real-world conditions of clinical care delivery. As a result, these trials yield findings that are highly generalizable to the nonresearch setting, identify interventions that are readily translatable into clinical practice, and cost less than trials that require extensive research infrastructures. Maintenance dialysis is a setting especially well suited for pragmatic trials because of inherently frequent and predictable patient encounters, highly granular and uniform data collection, use of electronic data systems, and delivery of care by a small number of provider organizations to approximately 90% of patients nationally. Recognizing the potential for pragmatic trials to generate much needed evidence to guide the care of patients receivin

SUBMITTER: Dember LM 

PROVIDER: S-EPMC5042681 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature