An iron-oxygen intermediate formed during the catalytic cycle of cysteine dioxygenase.

ABSTRACT: Cysteine dioxygenase is a key enzyme in the breakdown of cysteine, but its mechanism remains controversial. A combination of spectroscopic and computational studies provides the first evidence of a short-lived intermediate in the catalytic cycle. The intermediate decays within 20 ms and has absorption maxima at 500 and 640 nm.

SUBMITTER: Tchesnokov EP 

PROVIDER: S-EPMC5043143 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature