Autograft versus allograft in anterior cruciate ligament reconstruction: A meta-analysis with trial sequential analysis.

ABSTRACT:

Background

Anterior cruciate ligament (ACL) reconstruction is considered as the standard surgical procedure for the treatment of ACL tear. However, there is a crucial controversy in terms of whether to use autograft or allograft in ACL reconstruction. The purpose of this meta-analysis is to compare autograft with allograft for patients undergoing ACL reconstruction.

Methods

PubMed, EMBASE, and the Cochrane Library were searched for randomized controlled trials that compared autograft with allograft in ACL reconstruction up to January 31, 2016. The relative risk or mean difference with 95% confidence interval was calculated using either a fixed- or random-effects model. The risk of bias for individual studies according to the Cochrane Handbook. The trial sequential analysis w

SUBMITTER: Kan SL 

PROVIDER: S-EPMC5044918 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature