Cannabisol, a novel Δ⁹-THC dimer possessing a unique methylene bridge, isolated from Cannabis sativa.

ABSTRACT: Cannabisol (1), a unique dimer of Δ⁹-tetrahydrocannabinol (Δ⁹-THC) with a methylene bridge, was isolated from Cannabis sativa. This is the first example of a C-bridged dimeric cannabinoid. The structure of 1 was unambiguously deduced by HRESIMS, GCMS, and NMR spectroscopy. A plausible biogenesis of 1 is described.

SUBMITTER: Zulfiqar F 

PROVIDER: S-EPMC5045039 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature