Neural Activities Underlying the Feedback Express Salience Prediction Errors for Appetitive and Aversive Stimuli.

ABSTRACT: Feedback information is essential for us to adapt appropriately to the environment. The feedback-related negativity (FRN), a frontocentral negative deflection after the delivery of feedback, has been found to be larger for outcomes that are worse than expected, and it reflects a reward prediction error derived from the midbrain dopaminergic projections to the anterior cingulate cortex (ACC), as stated in reinforcement learning theory. In contrast, the prediction of response-outcome (PRO) model claims that the neural activity in the mediofrontal cortex (mPFC), especially the ACC, is sensitive to the violation of expectancy, irrespective of the valence of feedback. Additionally, increasing evidence has demonstrated significant activities in the striatum, anterior insula and occipital lobe fo

SUBMITTER: Gu Y 

PROVIDER: S-EPMC5046116 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature