Hypertension in pregnancy and risk of coronary heart disease and stroke: A prospective study in a large UK cohort.

ABSTRACT:

Background

Many studies investigating long-term vascular disease risk associated with hypertensive pregnancies examined risks in relatively young women among whom vascular disease is uncommon. We examined the prospective relation between a history of hypertension during pregnancy and coronary heart disease (CHD) and stroke in middle-aged UK women.

Methods

In 1996-2001, 1.1 million parous women (mean age=56years) without vascular disease at baseline reported their history of hypertension during pregnancy and other factors. They were followed for incident CHD and stroke (hospitalisation or death). Adjusted relative risks (RRs) were calculated using Cox regression.

Results

Twenty-six percent (290,008/1.1 million) reported having had a hypertensive pregnancy; 27% (79,163/

SUBMITTER: Canoy D 

PROVIDER: S-EPMC5047033 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature