Resting-State Functional MR Imaging for Determining Language Laterality in Intractable Epilepsy.

ABSTRACT: Purpose To measure the accuracy of resting-state functional magnetic resonance (MR) imaging in determining hemispheric language dominance in patients with medically intractable focal epilepsies against the results of an intracarotid amobarbital procedure (IAP). Materials and Methods This study was approved by the institutional review board, and all subjects gave signed informed consent. Data in 23 patients with medically intractable focal epilepsy were retrospectively analyzed. All 23 patients were candidates for epilepsy surgery and underwent both IAP and resting-state functional MR imaging as part of presurgical evaluation. Language dominance was determined from functional MR imaging data by calculating a laterality index (LI) after using independent component analysis. The accuracy of t

SUBMITTER: DeSalvo MN 

PROVIDER: S-EPMC5047125 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature