Introducing pharmacogenetic testing with clinical decision support into primary care: a feasibility study.

ABSTRACT:

Background

Inappropriate prescribing increases patient illness and death owing to adverse drug events. The inclusion of genetic information into primary care medication practices is one solution. Our aim was to assess the ability to obtain and genotype saliva samples and to determine the levels of use of a decision support tool that creates medication options adjusted for patient characteristics, drug-drug interactions and pharmacogenetics.

Methods

We conducted a cohort study in 6 primary care settings (5 family practices and 1 pharmacy), enrolling 191 adults with at least 1 of 10 common diseases. Saliva samples were obtained in the physician's office or pharmacy and sent to our laboratory, where DNA was extracted and genotyped and reports were generated. The reports were se

SUBMITTER: Dawes M 

PROVIDER: S-EPMC5047800 | biostudies-literature | 2016 Jul-Sep

REPOSITORIES: biostudies-literature