Genetic signals of high-altitude adaptation in amphibians: a comparative transcriptome analysis.

ABSTRACT:

Background

High-altitude adaptation provides an excellent system for studying how organisms cope with multiple environmental stressors and interacting genetic modifications. To explore the genetic basis of high-altitude adaptation in poikilothermic animals, we acquired transcriptome sequences from a high-altitude population and a low-altitude population of the Asiatic toad (Bufo gargarizans). Transcriptome data from another high-altitude amphibian, Rana kukunoris and its low-altitude relative R. chensiensis, which are from a previous study, were also incorporated into our comparative analysis.

Results

More than 40,000 transcripts were obtained from each transcriptome, and 5107 one-to-one orthologs were identified among the four taxa for comparative analysis. A total of 29 (B

SUBMITTER: Yang W 

PROVIDER: S-EPMC5048413 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature