Comorbid symptoms of emotional distress in adult survivors of childhood cancer.

ABSTRACT:

Background

Childhood cancer survivors are at risk for emotional distress symptoms, but symptom comorbidity has not been previously examined. This study examined distress profiles for adult survivors of childhood cancer diagnosed between 1970 and 1999.

Methods

Self-reported depression, anxiety, and somatization symptoms from Brief Symptom Inventory 18 were examined in survivors (n = 16,079) and siblings (n = 3085) from the Childhood Cancer Survivor Study. A latent profile analysis identified clusters of survivors with individual and comorbid symptoms. Disease, treatment, and demographic predictors of distress comorbidity patterns were examined with multinomial logistic regressions.

Results

Four clinically relevant profiles were identified: low distress on all subscales

SUBMITTER: D'Agostino NM 

PROVIDER: S-EPMC5048494 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature