Transmission of methicillin-resistant Staphylococcus aureus in long-term care facilities and their related healthcare networks.

ABSTRACT:

Background

Long-term care facilities (LTCF) are potential reservoirs for methicillin-resistant Staphylococcus aureus (MRSA), control of which may reduce MRSA transmission and infection elsewhere in the healthcare system. Whole-genome sequencing (WGS) has been used successfully to understand MRSA epidemiology and transmission in hospitals and has the potential to identify transmission between these and LTCF.

Methods

Two prospective observational studies of MRSA carriage were conducted in LTCF in England and Ireland. MRSA isolates were whole-genome sequenced and analyzed using established methods. Genomic data were available for MRSA isolated in the local healthcare systems (isolates submitted by hospitals and general practitioners).

Results

We sequenced a total of 181

SUBMITTER: Harrison EM 

PROVIDER: S-EPMC5048656 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature