Central aortic reservoir-wave analysis improves prediction of cardiovascular events in elderly hypertensives.

ABSTRACT: Several morphological parameters based on the central aortic pressure waveform are proposed as cardiovascular risk markers, yet no study has definitively demonstrated the incremental value of any waveform parameter in addition to currently accepted biomarkers in elderly, hypertensive patients. The reservoir-wave concept combines elements of wave transmission and Windkessel models of arterial pressure generation, defining an excess pressure superimposed on a background reservoir pressure. The utility of pressure rate constants derived from reservoir-wave analysis in prediction of cardiovascular events is unknown. Carotid blood pressure waveforms were measured prerandomization in a subset of 838 patients in the Second Australian National Blood Pressure Study. Reservoir-wave analysis was perf

SUBMITTER: Narayan O 

PROVIDER: S-EPMC5049681 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature