Determinants of the Transmission Variation of Hand, Foot and Mouth Disease in China.

ABSTRACT: Severe outbreaks of hand, foot and mouth disease (HFMD) have occurred in China for decades. Our understanding of the HFMD transmission process and its determinants is still limited. In this paper, factors that affect the local variation of HFMD transmission process were studied. Three classes of factors, including meteorological, demographic and public health intervention factors, were carefully selected and their effects on HFMD transmission were investigated with Pearson's correlation coefficient and multiple linear regression models. The determining factors for the variation of HFMD transmission were different for the southeastern and the northwestern regions of China. In the northwest, fadeouts occurred yearly, and the average age at infection and the fadeout were negatively correlated

SUBMITTER: Zhao J 

PROVIDER: S-EPMC5049751 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature