Effects of Bariatric Surgery on Renal Function in Obese Patients: A Systematic Review and Meta Analysis.

ABSTRACT:

Background

Obesity is an independent risk factor of development and progression of chronic kidney disease (CKD). Data on the benefits of bariatric surgery in obese patients with impaired kidney function have been conflicting.

Objective

To explore whether there is improvement in glomerular filtration rate (GFR), proteinuria or albuminuria after bariatric surgery.

Methods

We comprehensively searched the databases of MEDLINE, Embase, web of science and Cochrane for randomized, controlled trials and observational studies that examined bariatric surgery in obese subjects with impaired kidney function. Outcomes included the pre- and post-bariatric surgery GFR, proteinuria and albuminuria. In obese patients with hyperfiltration, we draw conclusions from studies using measure

SUBMITTER: Li K 

PROVIDER: S-EPMC5049777 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature