Associations between recent severe hypoglycemia, retinal vessel diameters, and cognition in adults with type 1 diabetes.

ABSTRACT:

Aims

Mild cognitive dysfunction has been identified in children and adults with type 1 diabetes, but most studies have failed to find a relationship between severe hypoglycemia and cognition, despite reports of such associations in older adults with type 2 diabetes. Focusing on older adults with type 1 diabetes, we examined the associations between cognitive performance and recent episodes of severe hypoglycemia, retinal vessel diameters and the presence of micro- and macrovascular complications.

Methods

Cognitive functioning was assessed in 244 participants enrolled in the Wisconsin Epidemiologic Study of Diabetic Retinopathy. The mean (SD; range) age at assessment in 2012-14 was 55.2 (8.3; 37-82) years and the mean (SD) duration of diabetes was 41.1 (5.6) years. Three cogn

SUBMITTER: Ryan CM 

PROVIDER: S-EPMC5050129 | biostudies-literature | 2016 Nov - Dec

REPOSITORIES: biostudies-literature