Ethnic Differences in Incidence and Outcomes of Childhood Nephrotic Syndrome.

ABSTRACT:

Background and objectives

Ethnic differences in outcomes among children with nephrotic syndrome are unknown.

Design, setting, participants, & measurements

We conducted a longitudinal study at a single regional pediatric center comparing ethnic differences in incidence from 2001 to 2011 census data and longitudinal outcomes, including relapse rates, time to first relapse, frequently relapsing disease, and use of cyclophosphamide. Among 711 children, 24% were European, 33% were South Asian, 10% were East/Southeast Asian, and 33% were of other origins.

Results

Over 10 years, the overall incidence increased from 1.99/100,000 to 4.71/100,000 among children ages 1-18 years old. In 2011, South Asians had a higher incidence rate ratio of 6.61 (95% confidence interval, 3.16 to

SUBMITTER: Banh THM 

PROVIDER: S-EPMC5053779 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature