Effect of Processing Delay and Storage Conditions on Urine Albumin-to-Creatinine Ratio.

ABSTRACT:

Background and objectives

Because there is substantial biologic intraindividual variation in albumin excretion, randomized trials of albuminuria-reducing therapies may need multiple urine samples to estimate daily urinary albumin excretion. Mailing spot urine samples could offer a convenient and cost-effective method to collect multiple samples, but urine albumin-to-creatinine ratio stability in samples stored at ambient temperatures for several days is unknown.

Design, setting, participants, & measurements

Patients with kidney disease provided fresh urine samples in two tubes (with and without boric acid preservative). Reference aliquots from each participant were analyzed immediately, whereas remaining aliquots were subject to different handling/storage conditions before a

SUBMITTER: Herrington W 

PROVIDER: S-EPMC5053802 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature