Comparison of photopic negative response measurements in the time and time-frequency domains.

ABSTRACT:

Purpose

To compare measurements of the full-field photopic negative response (PhNR), as well as intra-subject variation in the PhNR, using time and time-frequency domain analyses.

Methods

Full-field ERGs were recorded from 20 normally sighted subjects (aged 24-65 years) elicited by a long-wavelength pulse (3 cd s m^-2) presented against a short-wavelength adapting field (12.5 cd m^-2). Three to 10 waveforms were obtained from each subject, and each waveform was analyzed using standard time domain analyses of the PhNR, as well as a discrete wavelet transform (DWT) to extract time-frequency components that correspond to the PhNR. Three different measures of the PhNR were derived and compared: (1) amplitude at the PhNR trough; (2) amplitude at 72 ms followin

SUBMITTER: Kundra H 

PROVIDER: S-EPMC5053889 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature