MotViz: a tool for sequence motif prediction in parallel to structural visualization and analyses.

ABSTRACT: Linking similar proteins structurally is a challenging task that may help in finding the novel members of a protein family. In this respect, identification of conserved sequence can facilitate understanding and classifying the exact role of proteins. However, the exact role of these conserved elements cannot be elucidated without structural and physiochemical information. In this work, we present a novel desktop application MotViz designed for searching and analyzing the conserved sequence segments within protein structure. With MotViz, the user can extract a complete list of sequence motifs from loaded 3D structures, annotate the motifs structurally and analyze their physiochemical properties. The conservation value calculated for an individual motif can be visualized graphically. To chec

SUBMITTER: Nawaz MS 

PROVIDER: S-EPMC5054496 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature