Shotgun proteomic analysis of Yersinia ruckeri strains under normal and iron-limited conditions.

ABSTRACT: Yersinia ruckeri is the causative agent of enteric redmouth disease of fish that causes significant economic losses, particularly in salmonids. Bacterial pathogens differentially express proteins in the host during the infection process, and under certain environmental conditions. Iron is an essential nutrient for many cellular processes and is involved in host sensing and virulence regulation in many bacteria. Little is known about proteomics expression of Y. ruckeri in response to iron-limited conditions. Here, we present whole cell protein identification and quantification for two motile and two non-motile strains of Y. ruckeri cultured in vitro under iron-sufficient and iron-limited conditions, using a shotgun proteomic approach. Label-free, gel-free quantification was performed using

SUBMITTER: Kumar G 

PROVIDER: S-EPMC5054536 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature