Finding the shortest path with PesCa: a tool for network reconstruction.

ABSTRACT: Network analysis is of growing interest in several fields ranging from economics to biology. Several methods have been developed to investigate different properties of physical networks abstracted as graphs, including quantification of specific topological properties, contextual data enrichment, simulation of pathway dynamics and visual representation. In this context, the PesCa app for the Cytoscape network analysis environment is specifically designed to help researchers infer and manipulate networks based on the shortest path principle. PesCa offers different algorithms allowing network reconstruction and analysis starting from a list of genes, proteins and in general a set of interconnected nodes. The app is useful in the early stage of network analysis, i.e. to create networks or gene

SUBMITTER: Scardoni G 

PROVIDER: S-EPMC5054806 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature